Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPP2 All Species: 30.61
Human Site: S183 Identified Species: 51.79
UniProt: P29144 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29144 NP_003282.2 1249 138350 S183 S Q V E L L N S F E K K Y S D
Chimpanzee Pan troglodytes XP_001151602 1249 138350 S183 S Q V E L L N S F E K K Y S D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64514 1262 139860 S183 S Q V E L L N S F E K K Y S D
Rat Rattus norvegicus Q64560 1249 138274 S183 S Q V E L L N S F E K K Y S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513544 1367 152093 S288 S Q V E L L N S F E K K F N D
Chicken Gallus gallus XP_425591 1248 138209 S182 N Q V E L L N S F E K K Y S D
Frog Xenopus laevis NP_001085380 1261 139671 S182 S Q V E M L N S F E K K Y C D
Zebra Danio Brachydanio rerio XP_693179 595 63935
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V6K1 1441 158719 S280 F E L E M L N S Y E K V Y G D
Honey Bee Apis mellifera XP_395521 1450 161968 N183 A R V E I L N N I E K K Y S D
Nematode Worm Caenorhab. elegans Q09541 1374 151070 K233 A C K V D F L K S M A S V A D
Sea Urchin Strong. purpuratus XP_788834 1215 133209 N183 A M L D V L N N A D K K Y S D
Poplar Tree Populus trichocarpa XP_002318216 1299 143140 K205 N R I D L L R K Q A D V Y D D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193817 1380 152349 K285 S K V D F L K K Q A D K Y E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. N.A. N.A. 95.3 96.8 N.A. 81.2 86 80.4 37.7 N.A. 34 41.3 35 54.7
Protein Similarity: 100 99.7 N.A. N.A. N.A. 97.4 98.7 N.A. 86.6 94.6 91.3 43.1 N.A. 53 59.2 53.4 71.6
P-Site Identity: 100 100 N.A. N.A. N.A. 100 100 N.A. 86.6 93.3 86.6 0 N.A. 53.3 66.6 6.6 46.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 100 N.A. 100 100 93.3 0 N.A. 80 93.3 20 86.6
Percent
Protein Identity: 38 N.A. N.A. 37.4 N.A. N.A.
Protein Similarity: 56.9 N.A. N.A. 54.1 N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. 40 N.A. N.A.
P-Site Similarity: 53.3 N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 0 0 0 0 8 15 8 0 0 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 22 8 0 0 0 0 8 15 0 0 8 93 % D
% Glu: 0 8 0 65 0 0 0 0 0 65 0 0 0 8 0 % E
% Phe: 8 0 0 0 8 8 0 0 50 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 8 22 0 0 72 72 0 0 0 % K
% Leu: 0 0 15 0 50 86 8 0 0 0 0 0 0 0 0 % L
% Met: 0 8 0 0 15 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 15 0 0 0 0 0 72 15 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 50 0 0 0 0 0 0 15 0 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 0 0 0 0 0 58 8 0 0 8 0 50 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 65 8 8 0 0 0 0 0 0 15 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 79 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _